patient-derived cell model screening service

Progress your lead agent to clinical candidate with confidence

predictTx Screen is Imagen’s unique Patient-Derived Cell (PDC) model screen that leverages the power of high-content imaging to provide key information on the cytotoxicity and chemotherapeutic potential of your agent early in the drug development process.

Why use predictTx Screen

• Test your target hypothesis
• Identify responder populations
• Investigate mechanism of action
• Validate efficacy and cytotoxicity

Benefit from:

• Cost efficient screening service compared to stand-alone studies
• Simple model selection from a panel of 50 well-characterised PDCs across 18 different solid tumour types
• Model characterisation data including NGS, patient treatment history, in vitro drug response to standard of care
• Proven predictive power over patient response in the clinic
• Fast data turnaround
• Scalable patient-derived models for dose escalation and repeat studies
• Amenable to small molecule and biotherapeutics screening